INFLUENCE OF BASIC DENTAL PLASTICS ON BLOOD INDICATORS OF WHITE RATS (EXPERIMENTAL STUDY)

  • V.S. Kuz Higher State Educational Establishment of Ukraine "Ukrainian Medical Stomatological Academy"
  • V.N. Dvornyk Higher State Educational Establishment of Ukraine "Ukrainian Medical Stomatological Academy"
  • G.M. Kuz Higher State Educational Establishment of Ukraine "Ukrainian Medical Stomatological Academy"
  • O.Ye. Akimov Higher State Educational Establishment of Ukraine "Ukrainian Medical Stomatological Academy"
Keywords: dental plastics, blood counts, «Ftorax», «Deflex Acrylato», «Vertex ThermoSens».

Abstract

Background. Basic materials used in the clinic of orthopedic dentistry are high-polymer compounds and have a number of positive properties in certain conditions. The main group of materials for manufacturing of removable dentures is acrylic plastics of hot polymerization. However, such materials can sometimes cause a number of complications. Using removable prostheses, made of acrylic plastics can cause the development of an allergic or toxic-chemical reaction of tissues of the prosthetic bed.

The question of improving the quality of removable prosthesis is one of the most important problems for many years because of reactions of people’s organism they can cause. This aim is achieved by development of new basic dental materials and improvements at various stages of the process of manufacturing removable plate prostheses.

The aim is to investigate the possible adverse effect of various groups of basic dental materials on some hematological parameters of white male rats in the Wistar line.

Material and methods. Experiments were performed on 20 white male Wistar rats weighing 160-200 grams. The choice of this species was based on the literature data on the use of white rats in the study of the biological effects of plastics, solvents, dyes, and others.

Freshly made samples of the studied materials were used in experiments, because the maximum allocation of monomer occurs in the first 7 days after polymerization.

Euthanasia of animals was performed 7 days after surgical intervention under hexenal anesthesia by blood transfusion from the right ventricle. The object of the study was the venous blood of experimental animals.

Results. On the seventh day after substrate samples of basic materials Ftorax, Deflex Acrylato and Vertex ThermoSens intramuscularly into the anterior abdominal wall, white laboratory rats did not have results, such as some unnormal reaction of the animal's organism. A slight increase in the value of the index of spontaneous hemolysis of erythrocytes (5.8±0.5%) in the group of animals, which was sampled with the material "Ftorax" in comparison with the control group (4.6±0.3%), do not have statistically significant difference. Similarly, there is no significant increase in the accumulation of TBC-reactants in this group to a value of 4.48±0.28 μmol/l compared with the group of pseudo-operated animals (3.02±0.41 μmol/l), which is not statistically significant. Thus, it can be stated that according to the parameters of free radical oxidation, the biological reaction of the animal organism to the incorporation of the aforementioned materials was not revealed.

Conclusion. The results of the study of the biological effect of basic dental plastics on white rats by stacking samples of investigated material into the anterior abdominal wall evaluated by free radical oxidation and activity of antioxidant enzymes did not reveal statistically significant differences comparing with the control group of animals.

Downloads

Download data is not yet available.

References

1. Брусов О.С. Влияние природных ингибиторов радикальных реакций на автоокисление адреналина / О.С. Брусов, А.М. Герасимов, Л.Ф. Панченко // Бюл. эксперим. биол. мед. – 1976. – №1. – C.33-35.

2. Гожая Л.Д. Аллергические заболевания в ортопедической стоматологии / Л.Д. Гожая. – М.: Медицина, 1988. – 160 с.

3. Повышение качества полного съемного протезирования стоматологических больных путем использования новых базисных материалов / В.С. Кузь, В.Н. Дворник, А.И. Тесленко [ и др.] // Widamości Lekarskie: Czasopismo Polskiego Towarzystwa Lekarskiego. – 2016. – T. LXIX, Nr 2 (cz. II). – С. 197-203.

4. Кузь В.С. Використання сучасних безакрилових базисних матеріалів у клініці ортопедичної стоматології / В.С. Кузь, В.М. Дворник, Г.М. Кузь // Український стоматологічний альманах. – 2016. – №3, т. 2. – С. 40-46.

5. Кузь В.С. Відновлення жувальної ефективності у пацієнтів з повними знімними протезами, виготовленими з різних груп базисних матеріалів / В.С. Кузь, В.М. Дворник, Г.М. Кузь // Актуальні проблеми сучасної медицини: Вісник УМСА. – 2017. – Т. 17, вип. 3 (59). – С. 224-226.

6. Мачоган В.Р. Вплив базисних стоматологічних пластмас на гематологічні показники крові тварин / В.Р. Мачоган, В.Є. Пудяк, Р.Р. Мачоган // Клінічна стоматологія. – 2015. – № 1. – С. 21-23.

7. Методи клінічних та експериментальних досліджень в медицині / [Л.В. Беркало, О.В. Бобович, Н.О. Боброва та ін.]; за ред. І.П. Кайдашева. – Полтава, 2003. – 320 с.

8. Покровский A.A. К вопросу о перекисной резистентности эритроцитов // A.A. Покровский, А.А. Абраров // Вопросы питания. – 1964. – № 6. – С. 44-46.

9. Ортопедическая стоматология / [А.С. Щербаков, Е.Н. Гаврилов, В.Н. Трезубов, Е.Н. Жулев]. – СПб., 1997. – 566 с.
Published
2018-03-21
How to Cite
Kuz, V., Dvornyk, V., Kuz, G., & Akimov, O. (2018). INFLUENCE OF BASIC DENTAL PLASTICS ON BLOOD INDICATORS OF WHITE RATS (EXPERIMENTAL STUDY). Ukrainian Dental Almanac, (4), 5-8. Retrieved from https://dental-almanac.org/index.php/journal/article/view/286
Section
EXPERIMENTAL-THEORETICAL SECTION