TY - JOUR AU - Popelo, Yu.V. PY - 2018/03/21 Y2 - 2024/03/29 TI - DENTAL STATUS IN CHILDREN WITH MALIGNANT SOLID NEOPLASMS JF - Ukrainian Dental Almanac JA - Ukr. Dent. Alm. VL - 0 IS - 2 SE - CHILDHOOD STOMATOLOGY DO - UR - https://dental-almanac.org/index.php/journal/article/view/162 SP - 67-71 AB - Recently, a number of scientific researches were aimed at studying the structure of dental pathology associated with common somatic illnesses or developed under the influence of harmful factors. The special attention is given to patients of cancer who require the long-term special treatment under the current protocol, where one of the mandatory items applies to providing them the dental care, the amount of which may be determined only after ascertaining components that characterize the dental status.The urgency of this issue is due to a pronounced tendency to a rapid increase in the prevalence of disease with malignant formation, which requires a detailed study of the efficiency of already implemented methods and improving or developing new schemes for the sustainable maintenance of dental health in patients of this profile.Purpose of researches: to study the dental status of children with malignant tumors on the background of the toxic effects of chemotherapy drugs on improving measures to improve their dental health.Materials and methods. We have conducted the clinical examination of 31 children aged from 7 to 16 years with malignant solid tumors of the soft tissues of a varying anatomic localization. The research was conducted before and during the completion of the first and second courses of chemotherapy, and the break between them lasted for 3 weeks. The control group consisted of 25 healthy children of the same age.To analyze the dental status changes in the dynamics of chemotherapy it was used digital value codes the intensity of caries, Green- Vermillion (1964), PBI (Papilla Bleeding Index H.P. Muhlemann (1977).Results of researches and discussion. An objective examination of the dental status during hospitalization found out that the intensity of caries in pediatric patients was 1,67 ± 0,04 in milk teeth and 2,25 ± 0,06 –in a constant that according to WHO criteria is rated as "low" The Green-Vermillion index equaled 1,13 ± 0,04, with 0,52 ± 0,02 in the control group. Researching the state of periodontal tissues indicated for the initial signs of the inflammation of the marginal edge of the gums. Defining index RVI (Papilla Bleeding Index H.P. Muhlemann, 1977) showed 100% prevalence of gingival bleeding in a group of sickly children, the generalizing intensity of which was 0,92 ± 0,02 points.Further the comparative analysis of the results has determined a significant increase of the health index (Green- Vermillion), papillary, marginally-alveolar and bleeding index (PBI for H.P. Muhlemann) on the background of chemotherapy with maximum values for the period of ending the second course that it objectively coordinated with deterioration of the hygienic condition of the oral cavity and spreading the inflammation in the periodontal tissues from interdental papilla sites on the mucosa of the alveolar process. It should be noted that the definition of digital oscillation of significances of the index estimation has an selective assessment that it is possible due to the individual sensitivity of individuals to cytostatic.Meanwhile, regardless of the period of the survey, indexes of caries intensity in pediatric patients answered a low level and unchanged without the statistically significant difference.Conclusion. Thus, we conducted researches of the dental status in children with malignant solid tumors of soft tissues and found out changes of indexes Green-Vermillion, PMA and PBI allows revealing that they are directly dependent on the number of cycles of chemotherapy.The changes in the dental status associated with the course of cancer pathology which are aggravated due to the toxic effects of cytostatic drugs require the proper correction and allow you to set the necessary amount of pathogenesis reasonable dental care.Perspectives. By this time, there are no highly efficient schemes for the prevention and treatment of the manifestations of the toxic effects of chemotherapy on organs and tissues of the mouth. Therefore, the results may serve as a basis for planning accompanying dental care, which is provided by the provisions of the "local protocols of medical care ..." and should be aimed at correcting pathological changes in the conditions of antineoplastic therapy in these patients. ER -